Environmental xenobiotics and reproductive toxicity
نویسندگان
چکیده
منابع مشابه
Environmental xenobiotics and male reproductive health
toxicants.3 Following the Seveso disaster in northern Italy in 1976, a remarkable increase in the proportion of girls was reported among offspring of heavily dioxin exposed men.4 Thus, the overarching question is not whether environmental chemicals may represent a hazard to male reproductive health, but how important this hazard at exposure levels found in the general population is in compariso...
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The alternatives to whole-animal testing include endpoint assays, cell and tissue cultures, use of tissue slices, toxicokinetic modelling, and structure-activity relationships and databases. The use of in vitro systems (subcellular fractions, cell lines, primary cell cultures, tissue slices, organ cultures, etc.) as research tools in toxicology is widespread. In the past few years, the apoptosi...
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This review provides background information on the importance of bioremediation approaches. It describes the roles of fungi, specifically white rot fungi, and their extracellular enzymes, laccases, ligninases, and peroxidises, in the degradation of xenobiotic compounds such as single and mixtures of pesticides. We discuss the importance of abiotic factors such as water potential, temperature, a...
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This is the report of the thirtieth of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAMs main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laborato...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2010
ISSN: 1663-9812
DOI: 10.3389/conf.fphar.2010.60.00120